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However, spironolactone does not directly address other PCOS concerns like weight, insulin resistance, irregular menstrual cycles, or ovulation

Unlike oral supplements that have to go through the digestive system before reaching the bloodstream, a vitamin B12 injection delivers the nutrient directly into the blood

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Given the risk that obesity represents to public health and the difficulty of achieving and maintaining weight loss via lifestyle changes alone, there is a need for pharmacological approaches to aid weight loss in some individuals

Apart from a few limited exceptions for state enforcement, the FDA has exclusive enforcement authority with respect to the FDCAs provisions